The ProteomeLab XL-A/XL-I in-solution characterization of proteins, oligomers, aggregates, particles, colloids, and small structures delivers accurate results you can rely on time and again. In-solution characterization allows for testing in native conditions, meaning you determine the sample testing environment that best suits your needs. The unique column-free separating technique of the ProteomeLab XL-A/XL-I measures the relative change in the distribution of molecular weights, providing an efficient way to measure heterogeneity, stoichiometry and self-associating systems. And, because the measurements are based on the first principles of thermodynamics and hydrodynamics, no standards or calibrations are required. As a result, you spend less time on setup and more time on discovery.

Our analytical ultracentrifuge platform offers a variety of customizable options, to meet your needs.  Sensitive absorbance optics enable analysis of most samples, and interference optics can be used for low concentrations.  Both systems can be implemented simultaneously, to maximize data acquisition in a single run.  Additionally, we offer two different rotor configurations, and a variety of cell types, to enable multiple experimental designs.  The wide range of rotational velocities also allow investigators to probe protein size, dimerization, and binding constants.

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