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The Leica FL400 in combination with the active substance 5-ALA helps to see the tumor more clearly for a more complete resection of malignant glioma, while sparing healthy brain tissue.
Before surgery, the patient drinks the 5-ALA solution. The aminolevulinic acid is absorbed by the cells in the body, whereas the glioma cells take up more and convert 5-ALA into the fluorescent PPIX. When illuminated under blue light the PPIX in the tumor glows an intense red, while the normal tissue appears blue.
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